By placing multi-stakeholder collaboration at the heart of innovation, Living Labs play a transformative role in addressing Health and Wellbeing challenges. They have the potential to make significant contributions in key areas such as cancer research, non-communicable diseases, and the wellbeing of children, adolescents, and older adults. Their role in clinical environments and medical services is equally crucial. By assessing the impact and envisioning the future of Living Labs, the conference seeks to drive forward research and innovation in Health and Wellbeing. In addition, the conference will foster discussions on innovative methodologies for stakeholder engagement, ethical considerations, and the challenges of data management in this domain.